Programme
Wednesday, 24 April 2024
| 8:00 | Transfer from Jülich |
| 8:30 | Registration |
| 9:00 | Welcome Address by Dr. Robert Speck, Jülich Supercomputing Centre |
| Chair: Alexander Schug | |
| I. Large Biomolecular Simulation | |
| 9:10 |
Helmut Grubmüller, MPI für Multidisziplinäre Naturwissenschaften Microtubules’ bends, cryo-cool ribosomes, and wet proteins |
| 9:50 |
Joanna Sulkowska, University of Warsaw Understanding the mysteries of non-trivial topology in proteins and RNA based on Deep Learning approach and structural biology methods |
| 10:30 | Coffee |
| II. Integrative Molecular Biology | |
| 11:10 |
Simon Ebbinghaus, Ruhr-Universität Bochum RNA and protein folding stability in cells and condensates |
| 11:50 |
Ulrike Rehbein, Universität Duisburg-Essen Stress granule proteins as integrators of metabolic signals at the lysosomes |
| 12:30 | Lunch |
| Chair: Paolo Carloni | |
| 14:00 |
Gerhard Hummer, MPI für Biophysik Simulations of large pores |
| 14:40 |
Jochen Hub, Universität des Saarlandes Hydration shell of proteins from molecular simulations and high-precision small-angle scattering data: effects of surface chemistry, temperature, and force fields |
| 15:20 |
Birgit Strodel, Forschungszentrum Jülich Journey through Amyloid Protein Structures: Mapping Conformational Changes from Disorder to Aggregation with MD Simulations |
| 16:00 | Coffee |
| 16:40 |
Michael Sattler, Technical University of Munich and Helmholtz Munich NMR and integrative structural biology to study dynamic molecular interactions - from molecular chaperones to splicing regulation |
| 17:20 |
Ben Schuler, Universität Zürich Probing the dynamics and interactions of disordered proteins with single-molecule spectroscopy: From disordered complexes to phase separation |
| 18:00 | Poster Session (odd) and Reception |
| 20:15 | Transfer to Jülich |
Thursday, 25 April 2024
| 8:45 | Transfer from Jülich |
| Chair: Giulia Rossetti | |
| 9:10 |
Richard Börner, Hochschule Mittweida FRET-guided integrative modelling of non-coding ribonucleic acids |
| 9:50 |
Michael Kovermann, Universität Konstanz Combining NMR spectroscopy with MD simulations to determine the conformational landscape of multi-domain proteins at atomic resolution |
| 10:30 | Coffee |
| III. Biomolecular Evolution and AI | |
| 11:10 |
Fabrizio Pucci, Université libre de Bruxelles Combining structural and coevolutionary information for protein design applications |
| 11:50 |
Olga Kalinina, Helmholtz-Institut für Pharmazeutische Forschung
Saarland Predicting functional effect of genetic variants and some issues with data leakage in biomedical research |
| 12:30 | Group Picture |
| 12:45 | Lunch |
| Chair: Birgit Strodel | |
| 14:00 |
Faruck Morcos, The University of Texas at Dallas Epistatic models and Latent Generative Landscapes of sequence space as roadmaps for protein functional diversity, evolution, and design |
| 14:40 |
Marialore Sulpizi, Ruhr-Universität Bochum Exploring nucleotides complexes in solutions from spectroscopy and ab initio simulations |
| 15:20 |
José Onuchic, Rice University The three-dimensional architecture of the human genome: understanding the physical mechanisms controlling gene expression |
| 16:00 | Coffee |
| 16:40 |
Ines Heiland, The Arctic University of Norway Learning from evolution – from comparative genomics to physiology |
| 17:20 |
Martin Weigt, Sorbonne Université Protein evolution in sequence landscapes - from data to models and back |
| 18:00 | Poster Session (even) and Reception |
| 20:15 | Transfer to Jülich |
Friday, 26 April 2024
| 8:45 | Transfer from Jülich |
| Chair: Irene Vercellino | |
| VI. Protein Folding and Kinetics | |
| 9:10 |
Rebecca Wade, Heidelberger Institut für Theoretische Studien Towards predicting the effects of protein mutations on binding kinetics |
| 9:50 | Coffee / Guided Tour Jülich Supercomputing Centre |
| 10:50 |
Volkhard Helms, Universität des Saarlandes Role of accessory membrane proteins in protein translocation across the Sec61 channel |
| 11:30 |
Elsa Sanchez-Garcia, Technische Universität Dortmund From biomolecular simulations of nanostructures and function inhibition to machine learning tools for protein engineering |
| 12:10 |
Alexander Schug, Forschungszentrum Jülich Final Remarks and Poster Awards |
| 12:30 | Lunch |
| 14:00 | Transfer to Düren Train Station |
Last Modified: 31.01.2025
